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Sherine Elsawa

The neutral encyclopedia of notable people
Sherine Elsawa
OccupationImmunologist, academic
Alma materAlexandria University; Florida International University; University of North Carolina at Charlotte

Sherine Elsawa is an immunologist and Associate Professor in the Department of Molecular, Cellular and Biomedical Sciences at the University of New Hampshire.[1] Her research addresses the tumor microenvironment, innate inflammatory signaling, and the role of GLI transcription factors in cancer and immune function.[2]

Education

Elsawa received a B.Sc. in agronomy from Alexandria University in 1992.[3] She earned an MS in biological sciences from Florida International University in 1998,[4] and a Ph.D. in biomedical sciences from the University of North Carolina at Charlotte in 2003.[5]

Career

Elsawa joined Northern Illinois University in 2011 as an Assistant Professor of Immunology in the Department of Biology, and was promoted to Associate Professor of Immunology in 2017.[6] In 2017, she moved to the University of New Hampshire as an Assistant Professor in the Department of Molecular, Cellular and Biomedical Sciences, and was promoted to Associate Professor in 2019, a position she continues to hold.[7]

Research

Elsawa's work has been supported by the National Institutes of Health through seven funded projects totaling $1,398,058.[8] Her funded research at the University of New Hampshire has examined the role of GLI2 in antibody production and the mechanisms by which TLR-TRIF signaling induces GLI3 to modulate innate inflammatory responses.[9]

According to Semantic Scholar, Elsawa has published 92 papers that have been cited a total of 3,078 times, giving her an h-index of 22.[10] Her research has covered topics including macrophage polarization, monocyte and dendritic cell biology in lymphoproliferative disorders, the role of sulfatase 2 in hepatocellular carcinoma, B-lymphocyte stimulator signaling in Waldenstrom macroglobulinemia, and MYC and IRF4 regulation in lymphoma.[11]

Selected publications

  • "Macrophage Polarization States in the Tumor Microenvironment" (2021), International Journal of Molecular Sciences[12]
  • "Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells" (2009), Blood[13]
  • "GLI3: a mediator of genetic diseases, development and cancer" (2020), Cell Communication and Signaling[14]
  • "The oncogenic effect of sulfatase 2 (SULF2) in human hepatocellular carcinoma is mediated in part by glypican 3 (GPC3)-dependent Wnt activation" (2010), Hepatology[15]
  • "B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia" (2006), Blood[16]
  • "Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors" (2019), Journal of Hematology & Oncology[17]
  • "Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity" (2011), Blood[18]
  • "Selective activation of TACI by syndecan-2" (2006), Blood[19]
  • "The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma" (2015), Blood[20]
  • "Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells" (2012), Journal of Biological Chemistry[21]
  1. ↑ University of New Hampshire faculty records.
  2. ↑ National Institutes of Health grant records.
  3. ↑ ORCID record 0000-0002-3917-3078.
  4. ↑ ORCID record 0000-0002-3917-3078.
  5. ↑ ORCID record 0000-0002-3917-3928.
  6. ↑ ORCID record 0000-0002-3917-3078.
  7. ↑ ORCID record 0000-0002-3917-3078.
  8. ↑ National Institutes of Health grant records.
  9. ↑ National Institutes of Health grant records.
  10. ↑ Semantic Scholar author metrics.
  11. ↑ Semantic Scholar author metrics.
  12. ↑ Semantic Scholar author metrics.
  13. ↑ Semantic Scholar author metrics.
  14. ↑ Semantic Scholar author metrics.
  15. ↑ Semantic Scholar author metrics.
  16. ↑ Semantic Scholar author metrics.
  17. ↑ Semantic Scholar author metrics.
  18. ↑ Semantic Scholar author metrics.
  19. ↑ Semantic Scholar author metrics.
  20. ↑ Semantic Scholar author metrics.
  21. ↑ Semantic Scholar author metrics.
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