Beth Bouchard
| Beth Bouchard | |
| Known for | Research on platelet function and trauma-induced coagulopathy |
|---|---|
Beth Bouchard is a researcher at the University of Vermont whose work focuses on platelet biology, coagulation, and trauma-induced coagulopathy.
Research
Bouchard's publication record, as indexed by Semantic Scholar, includes 57 papers with a combined total of 1,988 citations and an h-index of 21.[1] Her work has examined the mechanisms of platelet trafficking and endocytosis, the role of histones and endotheliopathy in severe illness, and coagulation abnormalities following trauma.
Among her most cited studies is "Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions," published in Blood in 2017, which has been cited 48 times.[2] Related work published in the Journal of Trauma and Acute Care Surgery in 2017, "Microparticles Formed During Storage of Red Blood Cell Units Support Thrombin Generation," has been cited 29 times.[3]
During the COVID-19 pandemic, Bouchard contributed to studies on histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19, as well as on the use of the drug suramin to neutralize histones and prevent endotheliopathy, both posted on bioRxiv in 2021.[4][5]
According to National Institutes of Health records, Bouchard has been associated with 32 funded projects totaling $10,827,114. These include "MedSupport: A Novel Multilevel Intervention to Identify and Address Barriers to Pediatric Medication," administered through Roswell Park Cancer Institute Corp, which received awards of $640,437 and $31,622, and "Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence," also administered through Roswell Park Cancer Institute Corp, which received $632,198.[6]
Selected publications
- "Plasma-based assays distinguish hyperfibrinolysis and shutdown subgroups in trauma-induced coagulopathy," Journal of Trauma and Acute Care Surgery (2022)
- "Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19," bioRxiv (2021)
- "The polyanionic drug suramin neutralizes histones and prevents endotheliopathy," bioRxiv (2021)
- "Thrombin Formation," in Trauma Induced Coagulopathy (2020)
- "Detection of tissue factor in platelets: why is it so troublesome?," Platelets (2019)
- "Endocytosed factor V is trafficked to CD42b+ proplatelet extensions during differentiation of human umbilical cord blood‐derived megakaryocytes," Journal of Cellular Physiology (2018)
- "Venous thromboembolism, factor VIII and chronic kidney disease," Thrombosis Research (2018)
- "Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions," Blood (2017)
- "Microparticles Formed During Storage of Red Blood Cell Units Support Thrombin Generation," Journal of Trauma and Acute Care Surgery (2017)
External links
- ↑ Semantic Scholar author profile for Beth Bouchard.
- ↑ Semantic Scholar, "Cellubrevin/vesicle-associated membrane protein-3-mediated endocytosis and trafficking regulate platelet functions" (2017).
- ↑ Semantic Scholar, "Microparticles Formed During Storage of Red Blood Cell Units Support Thrombin Generation" (2017).
- ↑ Semantic Scholar, "Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19" (2021).
- ↑ Semantic Scholar, "The polyanionic drug suramin neutralizes histones and prevents endotheliopathy" (2021).
- ↑ National Institutes of Health, RePORTER database, grant records for Beth Bouchard.