Amber Doiron
| Amber Doiron | |
| Nationality | American |
|---|---|
| Occupation | Biomedical engineer, academic |
| Alma mater | Colorado State University (B.S.) University of Texas at Austin (M.S., Ph.D.) |
Amber Doiron is a biomedical engineer and academic at the University of Vermont, where she is an Assistant Professor in the Department of Electrical and Biomedical Engineering.[1] Her research addresses nanoparticle-based imaging contrast agents and strategies for disrupting bacterial biofilms.[2]
Education
Doiron received a B.S. in Chemistry from Colorado State University, completed between 1999 and 2003.[3] She then earned an M.S. and Ph.D. in Biomedical Engineering from the University of Texas at Austin, completed between 2004 and 2008.[4]
Career
Doiron carried out postdoctoral research at the University of Calgary in the Departments of Chemical Engineering and Radiology from 2009 to 2012.[5] She then joined Binghamton University as an Assistant Professor of Biomedical Engineering, a position she held from 2012 to 2018.[6] In 2018, she moved to the University of Vermont, where she has served as an Assistant Professor in the Department of Electrical and Biomedical Engineering.[7]
Research
Doiron's published work includes studies on gold nanoparticles as contrast agents for X-ray, CT, and multimodal imaging, and on the use of nanoparticles in the treatment of biofilms.[8] Her work on pyruvate-depleting conditions to induce biofilm dispersion and enhance antibiotic efficacy has been published in Scientific Reports.[9] She has also studied poly(lactic-co-glycolic) acid and gadolinium-DTPA-loaded biodegradable particles as carriers for imaging contrast agents, as well as the effects of nanoparticle exposure on endothelial barrier function and nanoparticle localization in blood vessels under varying fluid shear conditions.[10]
According to Semantic Scholar, her published output totals 43 papers with 821 citations and an h-index of 16.[11]
Doiron received a National Science Foundation CAREER award for a project titled "Metabolite-Depleting Materials as an Anti-Biofilms Strategy," awarded to the University of Vermont & State Agricultural College on January 16, 2024, totaling $351,294.[12] National Institutes of Health records show she received three project grants totaling $705,054 while at Binghamton University, including work on pyruvate depletion as adjunctive therapy for biofilm-related infections and on an iron oxide based polymer nanocomplex for functional detection of atherosclerosis.[13]
Selected publications
- Gold Nanoparticles as X-Ray, CT, and Multimodal Imaging Contrast Agents: Formulation, Targeting, and Methodology (2018)[14]
- Recent developments in the use of nanoparticles for treatment of biofilms (2017)[15]
- Pyruvate-depleting conditions induce biofilm dispersion and enhance the efficacy of antibiotics in killing biofilms in vitro and in vivo, Scientific Reports (2019)[16]
- Poly(Lactic-co-Glycolic) Acid as a Carrier for Imaging Contrast Agents, Pharmaceutical Research (2008)[17]
- Nanoparticle-Based Strategies for Managing Biofilm Infections in Wounds: A Comprehensive Review, ACS Omega (2024)[18]
- Preparation and initial characterization of biodegradable particles containing gadolinium-DTPA contrast agent for enhanced MRI, Proceedings of the National Academy of Sciences of the United States of America (2008)[19]
- Nanoparticle localization in blood vessels: dependence on fluid shear stress, flow disturbances, and flow-induced changes in endothelial physiology, Nanoscale (2018)[20]
- Endothelial nanoparticle binding kinetics are matrix and size dependent, Biotechnology and Bioengineering (2011)[21]
- Endothelial barrier dysfunction induced by nanoparticle exposure through actin remodeling via caveolae/raft-regulated calcium signalling, NanoImpact (2018)[22]
- Nanoparticle size-specific actin rearrangement and barrier dysfunction of endothelial cells, Nanotoxicology (2017)[23]
External links
- ↑ University of Vermont faculty records
- ↑ Semantic Scholar publication records
- ↑ ORCID record 0000-0002-6963-0989
- ↑ ORCID record 0000-0002-6963-0989
- ↑ ORCID record 0000-0002-6963-0989
- ↑ ORCID record 0000-0002-6963-0989
- ↑ ORCID record 0000-0002-6963-0989
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar author metrics
- ↑ National Science Foundation award records
- ↑ National Institutes of Health award records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records
- ↑ Semantic Scholar publication records