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Alice Bruce

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Alice Bruce
NationalityAmerican
OccupationChemist
Alma materColumbia University

Alice Bruce is an American chemist and professor of chemistry at the University of Maine. Her research has focused on the coordination chemistry of gold(I) complexes, including their electronic spectroscopy, structure, and applications relevant to antiarthritic gold drugs.[1]

Education

Bruce received her PhD in chemistry from Columbia College at Columbia University.[2]

Career

Bruce is a professor of chemistry at the University of Maine.[3]

Research

Bruce's published work spans studies of dinuclear gold(I) complexes, including their gold(I)-gold(I) interactions in solution and in the solid state, examined through electronic spectroscopy and solid-state EXAFS and luminescence methods.[4][5] She has also studied the electrochemical and chemical oxidation of gold(I) thiolate phosphine complexes and the formation of gold clusters and disulfides, including work on the oxidation of the antiarthritic gold drug auranofin.[6][7] Her earlier research addressed the coordination chemistry of molybdenum with tetradentate ligands containing N,S-donor sets.[8][9] More recent work includes a collaborative study on metal complexes as antifungal agents, published in JACS Au.[10]

According to Semantic Scholar, Bruce has published 84 papers that have been cited a total of 1,305 times, with an h-index of 20.[11]

Her research has been supported by the National Science Foundation, including a grant for "US-Russia Cooperative Research: Designing Gold(I) Complexes for New Materials" ($46,063, awarded July 15, 1998) and a grant for "Synthesis and Reactivity of Low Valent Transition Metal Imido Complexes" ($12,000, awarded April 3, 1989), both at the University of Maine.[12] She has also received funding from the National Institutes of Health, including a Small Instrumentation Grant ($5,000) and a grant titled "Chemistry of Gold-I & Sulfur, Application to Arthritis" ($106,226), both at the University of Maine.[13]

Selected publications

  • "Synthesis, structure, and electronic spectroscopy of neutral, dinuclear gold(I) complexes. Gold(I)-gold(I) interactions in solution and in the solid state" (1993)
  • "Solid State EXAFS and Luminescence Studies of Neutral, Dinuclear Gold(I) Complexes. Gold(I)-Gold(I) Interactions in the Solid State" (1995)
  • "Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments." JACS Au (2022)
  • "Stripping analyses of mercury using gold electrodes: irreversible adsorption of mercury." Analytical Chemistry (1999)
  • "Preparations and properties of tripodal and linear tetradentate N,S-Donor ligands and their complexes containing the MoO22+ core" (1984)
  • "Investigations of the Coordination Chemistry of Molybdenum with Facultative Tetradentate Ligands Possessing N2S2 Donor Sets" (1982)
  • "A nonoctahedral dioxo molybdenum complex with a coordinated partial disulfide bond" (1980)
  • "Novel metallamacrocyclic gold(I) thiolate cluster complex: structure and luminescence of [Au9(mu-dppm)4(mu-p-tc)6](PF6)3." Chemical Communications (2005)
  • "Electrochemical and Chemical Oxidation of Gold(I) Thiolate Phosphine Complexes: Formation of Gold Clusters and Disulfide" (1999)
  • "Formation of a cationic gold(I) complex and disulfide by oxidation of the antiarthritic gold drug auranofin." Inorganic Chemistry (2003)
  1. ↑ Semantic Scholar author profile, Alice Bruce.
  2. ↑ ORCID record 0000-0002-4556-8180.
  3. ↑ ORCID record 0000-0002-4556-8180.
  4. ↑ Bruce, A. et al. "Synthesis, structure, and electronic spectroscopy of neutral, dinuclear gold(I) complexes. Gold(I)-gold(I) interactions in solution and in the solid state" (1993).
  5. ↑ Bruce, A. et al. "Solid State EXAFS and Luminescence Studies of Neutral, Dinuclear Gold(I) Complexes. Gold(I)-Gold(I) Interactions in the Solid State" (1995).
  6. ↑ Bruce, A. et al. "Electrochemical and Chemical Oxidation of Gold(I) Thiolate Phosphine Complexes: Formation of Gold Clusters and Disulfide" (1999).
  7. ↑ Bruce, A. et al. "Formation of a cationic gold(I) complex and disulfide by oxidation of the antiarthritic gold drug auranofin." Inorganic Chemistry (2003).
  8. ↑ Bruce, A. et al. "Preparations and properties of tripodal and linear tetradentate N,S-Donor ligands and their complexes containing the MoO22+ core" (1984).
  9. ↑ Bruce, A. et al. "Investigations of the Coordination Chemistry of Molybdenum with Facultative Tetradentate Ligands Possessing N2S2 Donor Sets" (1982).
  10. ↑ "Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments." JACS Au (2022).
  11. ↑ Semantic Scholar author profile, Alice Bruce.
  12. ↑ National Science Foundation award records.
  13. ↑ National Institutes of Health award records.
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